Cardiac Biomechanics; Fiber Architecture; Finite Elements; Heart Failure; Patient-specific Models; Unloaded Geometry

Patient-specific models of cardiac biomechanics

Patient-specific models of cardiac function have the potential to improve diagnosis and management of heart disease by integrating medical images with heterogeneous clinical measurements subject to constraints imposed by physical first principles and prior experimental knowledge. We describe new methods for creating three-dimensional patient-specific models of ventricular biomechanics in the failing heart. Three-dimensional bi-ventricular geometry is segmented from cardiac CT images at end-diastole from patients with heart failure.

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