BioComLogo Bio-Thermo Database v1.00

X. Li1, R. K. Dash1, R. K. Pradhan1, F. Qi1, M. Thompson1,
K. C. Vinnakota1, F. Wu1, F. Yang2, and D. A. Beard1


1 Department of Physiology, Medical College of Wisconsin
2 Lilly-Singapore Centre for Drug Discovery Pte Ltd, Singapore


     This web base bio-thermodynamic database can be used to obtain the dissociation constants (provided as pK) and the corresponding dissociation enthalpies ΔrH0Kd for reference species associated with biochemical reactants at specified temperature and ionic strength.

Choosing reactant from the list below, the following constants of this reactant reference species
will be shown in the “Constants”.





Change to your experimental conditions,
click "Calculate New Constants", the new constant
of this reactant reference species will show in the
green fields

Temp. (K)
 
I (M)
 

New pK: N

Constants:

Abbreviation
Name
Name ΔfG0
(standard Gibbs free energy of reaction, T = 298.15K,
I = 0M)
Zia
(charge number of species i )
nH a
(number of protons in reference species)
   
   
             
pK_H1
(first ion dissociation constant of Hydrogan)
ΔΓHKd_H1
(first ion dissociation enthalpie of Hydrogen )
pk_H2
(second ion dissociation constant of Hydrogan)
ΔΓHKd_H2
(second ion dissociation enthalpie of Hydrogen )
pK_Mg1
(first ion dissociation constant of Magnesium)
ΔΓHKd_Mg1
(first ion dissociation enthalpie of Magnesium)
 
 
New pK:            
pK_HMg
(dissociation constant of Hydrogen and Magnesium)
ΔΓHKd_HMg
(dissociation enthalpie of Hydrogen and Magnesium)
pK_Mg2
(second ion dissociation constant of Magnesium)
ΔΓHKd_Mg2
(second ion dissociation enthalpie of Magnesium)
pK_K1
(first ion dissociation constant of Potassium)
ΔΓHKd_K1
(first ion dissociation enthalpie of Potassium)
 
 
             
pK_Na1
(first ion dissociation constant of Sodium)
ΔΓHKd_Na1
(first ion dissociation enthalpie of Sodium)
pK_HNa
(dissociation constant of Hydrogenand Sodium)
ΔΓHKd_HNa
(dissociation enthalpie of Hydrogen and Sodium)
pK_Ca1
(first ion dissociation constant of Calcium)
ΔΓHKd_Ca1
(first ion dissociation enthalpie of Calcium)
 
 
 
pK_HCa
(dissociation constant of Hydrogen and Calcium)
ΔΓHKd_Ca2
(second ion dissociation enthalpie of Calcium)
pK_Ca2
(Second ion dissociation constant of Calcium)
ΔΓHKd_Ca2
(second ion dissociation enthalpie of Calcium)
     
     

Corp Right 2010 @ Computational Bioengineering Group, Bioengineering and Biotechology Center, Medical College of Wisconsin