MathWorks Research Summit is an annual invitation-only event to meet inspiring peers from your and adjacent research areas and set directions that redefine the frontiers of research with impact and value. This multidisciplinary summit provides a forum for candid exchange with highly acclaimed thought leaders, industry and government experts, and MathWorks senior management about technical challenges, opportunities, and solution attempts to help focus and collaborate on promising research efforts. The summit features lively discussions interspersed with exciting technical talks to disseminate knowledge, germinate ideas, inspire applications, discover successes in related fields, recognize trends, and identify research needs. Participants can also socialize and network with people who govern professional organizations, have experience in organizing research programs and projects, and share guidance on workforce teaching and training. Dr. Beard gave a talk at the 2018 summit on the topic of cardiac work and metabolism. Cardiomyocytes (muscle cells that makes up the major portion of the walls of the heart) consume metabolic substrates (primarily carbohydrates and fats) to continuously produce adenosine triphosphate (ATP). The hydrolysis breakdown is, in turn, used to drive the electrical and mechanical function of the heart. Because metabolic demand for ATP production in the myocardium is proportional to cardiac work, and because ATP hydrolysis serves as the source of chemical-free energy to drive myocardial contraction, it stands to reason that limitations or impairments in myocardial energy metabolism may contribute to baseline and/or reserve cardiac power output.