Welcome to The Virtual Physiological Rat Project

The Virtual Physiological Rat Project aims to simulate the integrated cardiovascular function of the rat, and to build validated computer models that account for genetic variation across rat strains and physiological response to environment (i.e., diet). In addition, new strains of genetically engineered rat will be developed with the ultimate goal of using computer models to predict the physiological characteristics of not yet realized genetic combinations, derive those combinations in the lab, and then test the predictions.
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Recent News

The Virtual Rat Project has been featured in an article in SLAS Electronic Laboratory Neighborhood. Please check out "The Virtual Rat: Exploration of Complex Diseases Will Impact Drug Discovery, Development".

Summary:

Researchers around the world are spearheading an ambitious initiative aimed at understanding and predicting physiological function in health and disease. What’s unusual about this initiative is that the team—a network of investigators from the United States, Europe and New Zealand—isn’t simply running thousands of in vitro and in vivo experiments as they try to unearth the mechanisms underlying disease and dysfunction. Instead, they are working with computational tools and computer simulations based on the physiology of a rat.